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Related Concept Videos

Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

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Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
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Peripheral Artery Disease I: Introduction01:30

Peripheral Artery Disease I: Introduction

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Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
207
Diabetes: Symptoms, Diagnosis, and Complications01:15

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For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
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Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

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Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
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Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

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Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
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Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

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Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
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Related Experiment Video

Updated: Dec 17, 2025

Author Spotlight: Understanding Retinal Vessel Resilience and Disease Progression
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Author Spotlight: Understanding Retinal Vessel Resilience and Disease Progression

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[Diabetic macroangiopathy].

A F Verbovoy1, A V Pashentseva1, N I Verbovaya1

  • 1Samara State Medical University.

Terapevticheskii Arkhiv
|June 30, 2020
PubMed
Summary

Diabetes mellitus is a global health issue. Diabetic macroangiopathy, affecting heart and vessels, is a primary cause of disability and death in patients, requiring prompt medical intervention.

Area of Science:

  • Cardiology
  • Endocrinology
  • Public Health

Background:

  • Diabetes mellitus poses a significant global health challenge.
  • Diabetic macroangiopathy, encompassing heart and vessel damage, is a leading cause of morbidity and mortality in diabetic patients.
  • This vascular complication is frequently diagnosed at the time of diabetes mellitus diagnosis.

Purpose of the Study:

  • To highlight the critical impact of diabetic macroangiopathy.
  • To emphasize the need for early detection and active management of this complication.
  • To underscore the medico-social burden of diabetes mellitus.

Main Methods:

  • Literature review on diabetic macroangiopathy prevalence and impact.
  • Analysis of epidemiological data concerning diabetes-related mortality and invalidism.
Keywords:
coronary heart diseasediabetes mellitusdiabetic macroangiopathyobliterating atherosclerosis of arteries of the lower extremities

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  • Clinical case study review highlighting early diagnosis and treatment.

    • Main Results:

    • Diabetic macroangiopathy is a major contributor to disability and mortality in diabetes mellitus.
    • Early identification of vascular lesions is crucial for effective patient outcomes.
    • Proactive treatment strategies are essential to mitigate the severe consequences of diabetic macroangiopathy.

    Conclusions:

    • Diabetes mellitus necessitates comprehensive management strategies focusing on vascular health.
    • Addressing diabetic macroangiopathy is paramount to reducing patient invalidism and mortality.
    • Integrated healthcare approaches are vital for managing the medico-social impact of diabetes.