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Insomnia is a prevalent sleep disorder characterized by difficulty falling asleep, frequent awakenings during the night, and waking up too early without being able to return to sleep. People with insomnia often experience these disruptions at least three nights a week for at least one month. Chronic insomnia, which lasts for at least three months, can lead to increased anxiety, which in turn can worsen sleep difficulties, creating a cycle of sleeplessness and stress.
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The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
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Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
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Alterations in blood pressure, such as hypertension (high blood pressure) and hypotension (low blood pressure), significantly affect human health. Understanding these conditions' classifications, causes, and symptoms is essential for effective management and treatment.
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Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia
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[Hypertension and insomnia].

T M Ostroumova1, V A Parfenov1, O D Ostroumova1,2

  • 1Sechenov First Moscow State Medical University (Sechenov University).

Terapevticheskii Arkhiv
|June 30, 2020
PubMed
Summary
This summary is machine-generated.

Insomnia is common in arterial hypertension (AH) patients and may be a risk factor for developing high blood pressure. Studies show insomnia is linked to higher nocturnal blood pressure and poorer sleep quality in hypertensive individuals.

Keywords:
ambulatory blood pressure monitoringcognitive impairmenthypertensioninsomnia

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Area of Science:

  • Cardiology
  • Sleep Medicine
  • Neuroendocrinology

Background:

  • Insomnia is highly prevalent in patients with arterial hypertension (AH), affecting 19-47.9% of AH cases.
  • Conversely, hypertension is found in 21.4-50.2% of insomnia patients, compared to 11.0-41.8% without insomnia.
  • Emerging evidence suggests insomnia is an independent risk factor for developing hypertension.

Purpose of the Study:

  • To explore the intricate relationship between insomnia and arterial hypertension.
  • To discuss potential pathogenetic mechanisms linking these two conditions.
  • To examine the role of sleep quality and cognitive function in patients with both insomnia and hypertension.

Main Methods:

  • Epidemiological data analysis on the prevalence of insomnia in AH and vice versa.
  • Review of studies utilizing ambulatory blood pressure monitoring (ABPM) in insomnia patients.
  • Assessment of sleep quality using the Pittsburgh Sleep Quality Index (PSQI).

Main Results:

  • Insomnia patients exhibit higher nocturnal blood pressure levels.
  • Higher PSQI scores are observed in hypertensive patients compared to normotensive individuals.
  • PSQI scores correlate with elevated systolic and diastolic blood pressure and non-dipper profiles.

Conclusions:

  • The interplay between insomnia and hypertension involves neuroendocrine stress systems (sympatho-adrenal, hypothalamic-pituitary-adrenal) and anxiety.
  • Impaired sleep quality, as measured by PSQI, is associated with hypertension.
  • Both conditions are linked to cognitive impairment, though the relationship requires further clarification due to methodological variations.