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Related Concept Videos

Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

130
Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
130

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Histological Quantification of Chronic Myocardial Infarct in Rats
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[The myocardial infarction size measuring using modern methods].

E A Shigotarova1, V A Galimskaja2, A V Golubeva2

  • 1Burdenko Penza Oblast Clinical Hospital.

Terapevticheskii Arkhiv
|June 30, 2020
PubMed
Summary

Accurately quantifying myocardial infarction necrosis and viable zones is vital for patient selection and surgery outcomes. Monitoring these areas using non-invasive methods like electrocardiography and echocardiography remains crucial for predicting prognosis.

Keywords:
contrast magnetic resonance imaging of the heartechocardiographyelectrocardiogrammyocardial infarctionmyocardial necrosis areaspeckle trackingviable myocardium area

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Area of Science:

  • Cardiology
  • Medical Imaging
  • Cardiac Surgery

Background:

  • Accurate assessment of myocardial infarction necrosis and viable zones is critical for patient management.
  • The necrosis zone area directly correlates with patient prognosis and cardiac remodeling.
  • Monitoring both necrosis and viable zones dynamically is essential post-myocardial infarction.

Purpose of the Study:

  • To highlight the importance of quantifying myocardial infarction necrosis and viable zones.
  • To emphasize the prognostic significance of the necrosis zone.
  • To discuss the relevance of non-invasive methods for estimating necrotic myocardium area.

Main Methods:

  • Contrast-enhanced cardiac magnetic resonance imaging (MRI) is the most accurate method for necrosis area determination.
  • Electrocardiography (ECG) and echocardiography are explored as accessible, non-invasive alternatives.
  • The study reviews existing methods for assessing myocardial viability and necrosis.

Main Results:

  • The necrosis zone area is a key determinant of patient prognosis and pathological remodeling.
  • Viable myocardium zones (stunned and hibernating) are also important but secondary to necrosis for prognosis.
  • Contrast MRI, while accurate, has limited accessibility in clinical settings.

Conclusions:

  • Quantitative assessment of myocardial necrosis and viable zones is crucial for preoperative selection and predicting cardiac surgery effectiveness.
  • Estimating necrotic myocardium area using ubiquitous non-invasive methods like ECG and echocardiography remains a relevant clinical challenge.
  • Dynamic monitoring of necrosis and viable zones is necessary for predicting post-infarction outcomes and understanding arrhythmogenesis.