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VectorInfo: A web resource for medically important Indian arthropod disease vectors
Jeyakodi Gopal1, Thulasibabu Ramamoorthy2, Gunasekaran Kasinathan2
1Biomedical Informatics Centre, Vector Control Research Center, Indian Council of Medical Research, Pondicherry, 605006, India; Centre for Bioinformatics, Pondicherry University, Pondicherry, 605014, India.
Abstract:
VectorInfo is a freely accessible web resource, emphasised on medically important Indian arthropods funded by Indian Council of Medical Research (ICMR) and maintained by one of its premier institute, Vector Control Research Centre (VCRC). VectorInfo elucidates and curates medically important Indian arthropod's biological, omics technologies to adopt a holistic view of the molecules that make up an organism, aimed at the detection of genomics, transcriptomics, proteomics, enzymes & pathways and immune specific genes. The nitty-gritty of VectorInfo is aimed at scrutinizing all the possible information on Indian disease vectors in a single window for the scientific community. The database affords 53 medically important Indian arthropod's biological and omics information well-structured and provided with downloadable facilities. In addition to this, huge number of research articles were mined in the quest for gathering the recommended insecticide targets and their mechanisms, that pave ways to design and develop novel lead molecules through computational means. This current up-to-date database contains 2,498 omics entries beneficial for the molecular studies and analysis. In order to maintain regular updates, user forms were provided for the scientific community to submit research data to the database administrator. The VectorInfo furthermore conveys various resources for vector control and diagnostics and the links to the crucial software tools used for the Bioinformatics analysis.
Insights
VectorInfo is a free database detailing medically important Indian arthropods, offering biological and omics data for disease vector research. It supports the development of new insecticides and diagnostics for public health.
Area of Science:
- Medical Entomology
- Bioinformatics
- Genomics
Background:
- Medically important Indian arthropods pose significant public health challenges.
- Comprehensive, integrated data on these vectors is crucial for effective control strategies.
Purpose of the Study:
- To establish VectorInfo, a freely accessible web resource for Indian disease vectors.
- To consolidate biological and omics data for 53 medically important Indian arthropods.
- To facilitate research in genomics, transcriptomics, proteomics, and immune gene identification.
Main Methods:
- Curating biological and omics data (genomics, transcriptomics, proteomics) for Indian arthropods.
- Mining research articles to identify insecticide targets and mechanisms.
- Integrating data into a structured, downloadable database.
- Providing links to bioinformatics analysis tools.
Main Results:
- VectorInfo database now includes biological and omics information for 53 Indian arthropods.
- Contains 2,498 omics entries, supporting molecular studies.
- Identified potential insecticide targets and mechanisms for novel molecule development.
- Offers resources for vector control, diagnostics, and bioinformatics analysis.
Conclusions:
- VectorInfo serves as a centralized, valuable resource for researchers studying Indian disease vectors.
- The database supports the design of novel control strategies and therapeutic interventions.
- Facilitates advancements in bioinformatics and molecular analysis for vector-borne diseases.
