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Perspectives on somatic reprogramming: spotlighting epigenetic regulation and cellular heterogeneity

Jiekai Chen1

  • 1Key Laboratory of Regenerative Biology of the Chinese Academy of Sciences and Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 510530 Guangzhou, China; Guangzhou Regenerative Medicine and Health-Guangdong Laboratory (GRMH-GDL), 510530 Guangzhou, China.

Current Opinion in Genetics & Development
|June 30, 2020
PubMed
Summary

Somatic cell reprogramming reveals how cell fate can be reversed. Epigenetic regulation and cell heterogeneity are key to understanding cell fate determination and developmental programming.

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