[Intramyometrial PGF2 alpha administration in the control of severe atonic postpartum hemorrhage]

The authors report on five cases of massive atonic uterine haemorrhage which could be influenced neither by repeated application of oxytocin nor by methylergometrin. Intramyometrial application of PGF2 alpha succeeded in inducing a satisfactory uterine tone and stopping the haemorrhage. With regard to own experiences and data from only few publications dealing with the use of prostaglandin in atonic haemorrhage, the authors consider transvaginal intramyometrial application of PGF2 alpha to be an effective method to circumvent an emergency hysterectomy. However, this should occur sufficiently early and in a dose of not less than 1 mg.