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Concurrent Exercise Interventions in Breast Cancer Survivors with Cancer-related Fatigue.
Itiziar Pagola1, Javier S Morales1, Lidia B Alejo1
1Faculty of Sport Sciences, Universidad Europea de Madrid, Spain.
International Journal of Sports Medicine
|June 30, 2020
Summary
High-intensity concurrent training may improve muscle strength and fatigue in breast cancer survivors. While both high- and moderate-intensity programs showed no significant differences, high-intensity training demonstrated a trend toward improved fatigue perception.
Area of Science:
- Exercise Science
- Oncology Rehabilitation
- Cancer Survivorship
Background:
- Cancer-related fatigue significantly impacts breast cancer survivors' quality of life.
- Supervised concurrent training is a promising intervention for managing cancer-related fatigue.
- Comparing different exercise intensities is crucial for optimizing rehabilitation strategies.
Purpose of the Study:
- To compare the effects of high- vs. moderate-intensity supervised concurrent training on cancer-related fatigue in breast cancer survivors.
- To evaluate the impact of these interventions on muscle strength, body composition, and quality of life.
Main Methods:
- Twenty-three female breast cancer survivors with baseline fatigue were randomized into high-intensity (n=13) or moderate-intensity (n=10) training groups.
- Both 16-week programs included identical resistance exercises; aerobic intensity differed (RPE 7-8 vs. 6).
- Primary endpoint was fatigue perception, assessed at baseline and 16 weeks, with secondary outcomes including muscle strength and quality of life.
Main Results:
- High-intensity training significantly increased lower-limb muscle strength (p=0.002) and showed trends towards improved fatigue perception (p=0.006).
- Moderate-intensity training did not yield significant improvements.
- No statistically significant differences were found between the high- and moderate-intensity interventions (all p>0.004).
Conclusions:
- High-intensity concurrent training may offer benefits for muscle strength and fatigue perception in breast cancer survivors.
- Further research is required to determine if high-intensity training provides superior benefits compared to moderate-intensity training.
- Both training intensities were well-tolerated, highlighting the potential of exercise in cancer survivorship care.
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