Related Experiment Video
Updated: Dec 17, 2025

Culture of Bladder Cancer Organoids as Precision Medicine Tools
Published on: December 28, 2021
Urobiome in Gender-Related Diversities of Bladder Cancer
Konrad Bilski1, Jakub Dobruch1, Mieszko Kozikowski1
1Department of Urology, Centre of Postgraduate Medical Education, Independent Public Hospital of Professor W. Orlowski, 00-416 Warsaw, Poland.
Abstract:
Bladder cancer (BC) remains the most common malignancy of urinary tract. Sex-related differences in BC epidemiology, diagnosis, therapy, and outcomes have been reported. Throughout the recent years, extensive research has been devoted to genetic and molecular alterations in BC. Apart from the molecular background, another related concept which has been speculated to contribute to gender diversities in BC is the role of urinary pathogens in bladder carcinogenesis. Microbiome studies, fueled by the availability of high-throughput DNA-based techniques, have shown that perturbation in the microbiome is associated with various human diseases. The aim of this review is to comprehensively analyze the current literature according to sex-related differences in the microbiome composition in BC.
Related Concept Videos
Anatomy of the Genitourinary System II: Bladder and Urethra
Urinary Bladder
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
Nursing Assessment of the Genitourinary System I: Health History
Disorders of the Urinary System
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
Urinary Tract Infection II: Pathophysiology

