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Related Concept Videos

Computed Tomography01:10

Computed Tomography

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Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
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Related Experiment Video

Updated: Dec 17, 2025

Using Micro-computed Tomography for the Assessment of Tumor Development and Follow-up of Response to Treatment in a Mouse Model of Lung Cancer
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Surgical Outcomes in a Lung Cancer-Screening Program Using Low Dose Computed Tomography.

M Mesa-Guzmán1, J González2, A B Alcaide2

  • 1Departamento de Cirugía Torácica, Clínica Universidad de Navarra, Pamplona, Spain.

Archivos De Bronconeumologia
|July 1, 2020
PubMed
Summary
This summary is machine-generated.

Lung cancer screening in Spain demonstrated excellent surgical outcomes. Early detection via low-dose computed tomography (LDCT) led to high survival rates for operable lung cancer (LC).

Keywords:
CirugíaCribadoCáncer de pulmónLow-dose CTLung cancerP-IELCAPScreeningSupervivenciaSurgerySurvivalTomografía computarizada de baja dosis

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Area of Science:

  • Oncology
  • Thoracic Surgery
  • Radiology

Background:

  • Lung cancer (LC) is a leading cause of cancer death globally, with many cases in Spain diagnosed at unresectable stages.
  • Early detection and timely treatment are crucial for reducing LC mortality.
  • A longstanding lung cancer screening (LCS) program in Spain utilizes low-dose computed tomography (LDCT).

Purpose of the Study:

  • To describe the surgical outcomes within a well-established LC screening cohort in Spain.
  • To evaluate the effectiveness of LDCT-based screening in identifying operable lung cancers.
  • To analyze the morbidity, mortality, and survival associated with surgical treatment of screen-detected lung cancers.

Main Methods:

  • A retrospective analysis of surgical outcomes in an LCS program using LDCT since 2000.
  • Descriptive analysis of clinical, radiological, and pathological data, including preoperative diagnosis, staging, complications, and survival.
  • Evaluation of 87 surgical procedures for suspected or biopsy-proven LC detected by LDCT.

Main Results:

  • Ninety-seven lung cancers (2.5%) were diagnosed in 3825 screened individuals.
  • Eighty-seven surgical procedures were performed; most patients were male (85%), aged 64±9.1 years, with a mean tumor size of 15.2±7.6mm.
  • Stage I lung cancer (88%) was most common, with adenocarcinoma (58.2%) being the predominant histology. Five- and 10-year survival rates for stage I were 93% and 83%, respectively.

Conclusions:

  • Lung cancer screening using LDCT is associated with excellent surgical outcomes.
  • High survival rates (5-year >90%, 10-year >80%) were achieved for stage I lung cancer detected through screening.
  • The findings support the efficacy of LCS programs in improving survival for lung cancer patients.