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Updated: Dec 16, 2025

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
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Metabolic Resolution of Lytic Lesions in Erdheim-Chester Disease on 18F-FDG PET/CT

Divya Yadav1, Rachna Seth2, Shamim Ahmed Shamim1

  • 1From the Departments of Nuclear Medicine.

Clinical Nuclear Medicine
|July 1, 2020
PubMed

Insights

Erdheim-Chester disease (ECD) is a rare disorder affecting bones. Serial F-FDG PET/CT scans effectively assess treatment response in adolescent patients with ECD.

Area of Science:

  • Oncology
  • Radiology
  • Histiocytic Disorders

Background:

  • Erdheim-Chester disease (ECD) is a rare non-Langerhans cell histiocytosis.
  • It presents with diverse clinical manifestations, frequently impacting the skeletal system.

Observation:

  • The long bones are the most commonly affected sites in ECD.
  • Bone scintigraphy often reveals increased bilateral symmetric uptake in metadiaphyseal regions.

Findings:

  • This study details serial F-FDG PET/CT findings in a 16-year-old female adolescent diagnosed with ECD.
  • F-FDG PET/CT demonstrates significant utility in monitoring treatment efficacy for ECD.

Implications:

  • F-FDG PET/CT serves as a valuable tool for assessing therapeutic response in Erdheim-Chester disease.
  • This imaging modality aids in managing skeletal involvement in pediatric and adolescent ECD cases.

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