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A Morphometric and Cellular Analysis Method for the Murine Mandibular Condyle
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Morphometric Development of the Mandible in Fetal Cadavers
Yadigar Kastamoni1, Ahmet Dursun1, Onur Can Sanli1
1Department of Anatomy, Faculty of Medicine, Suleyman Demirel University, Isparta.
The Journal of Craniofacial Surgery
|July 1, 2020
Summary
This study measured fetal mandible morphometrics, finding that most parameters increase with development, except the mandibular angle which changes across trimesters. These findings offer valuable data for identifying developmental anomalies.
Area of Science:
- Anatomy
- Developmental Biology
- Anthropology
Background:
- The fetal mandible undergoes significant development.
- Understanding its morphometric properties is crucial for diagnosing congenital anomalies and variations.
Purpose of the Study:
- To provide reliable morphometric data of the fetal mandible.
- To establish normative values for mandibular parameters during fetal development.
Main Methods:
- A morphometric analysis was conducted on 35 fetal mandibles (21-40 weeks gestation).
- Measurements included mental foramen dimensions (digital caliper) and other parameters (ImageJ software).
- Data were analyzed using SPSS, comparing parameters across developmental stages (2nd trimester, 3rd trimester, full-term) and by gender.
Main Results:
- No significant gender-based differences were observed for any parameter.
- Most mandibular parameters increased with gestational age, except the angle of the mandible.
- The angle of the mandible showed a decrease from the 2nd to 3rd trimester and an increase from the 3rd trimester to full-term.
Conclusions:
- This study presents novel fetal mandibular morphometric data.
- The findings contribute to the assessment of fetal mandibular anomalies, pathologies, and variations.
- Normative data can aid in clinical diagnosis and forensic investigations.
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