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[Adoptive immunotherapy of malignant disease using LAK cells]
1Dept. of Oncologic Surgery, Research Institute for Microbial Diseases, Osaka University, Japan.
Gan to Kagaku Ryoho. Cancer & Chemotherapy
|April 1, 1988
Summary
Adoptive immunotherapy using lymphokine-activated killer (LAK) cells and interleukin-2 (IL-2) showed clinical effects against various cancers. Researchers found fever was the only side effect, but inducing sufficient LAK cells remains a challenge.
Area of Science:
- Immunology
- Oncology
- Cell Therapy
Background:
- Adoptive immunotherapy is a promising approach for malignant diseases.
- Lymphokine-activated killer (LAK) cells, induced by interleukin-2 (IL-2), are a key component of this therapy.