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Updated: Dec 16, 2025
Stereotactic Radiosurgery for Gynecologic Cancer
Published on: April 17, 2012
Hysterectomy for Recurrent/Residual Cervical Cancer Following Definitive Radiotherapy
Tadaharu Nakasone1, Yusuke Taira2, Yuko Shimoji2
1Department of Obstetrics and Gynecology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan miamiamia1229@gmail.com.
Background/Aim:
Radical hysterectomy has been used for local recurrent or persistent (LR) cervical cancer after radiotherapy (RT), but the rate of serious complications is high and tolerance is low. This study determined the efficacy, safety, and prognostic factors of adjuvant simple hysterectomy in LR cervical cancer post-RT.
Patients And Methods:
A total of 21 patients who underwent hysterectomy for LR cervical cancer post-RT in our Department between May 2007 and September 2018 were included in the study. Primary, definitive RT was performed. Histological response by definitive RT in the extirpated uterus was classified on the basis of histological response criteria: effect (Ef) 0-3.
Results:
The 5-year overall survival (OS) and disease-free survival (DFS) rates were 51.9% and 50.1%, respectively. Ef 1 was significantly associated with poorer prognosis compared to Ef 2 or Ef 3.
Conclusion:
Adjuvant hysterectomy could be a treatment of choice for LR cervical cancer post-RT.
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