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Minimally Invasive Gastric Electrical Stimulation Using a Newly Developed Wireless Gastrostimulator: A Pilot Animal

Seung Han Kim¹, Hong Bae Kim², Hoon Jai Chun¹

¹Division of Gastroenterology and Hepatology, Department of Internal Medicine, Institute of Gastrointestinal Medical Instrument Research, Korea University College of Medicine, Seoul, Korea.

Journal of Neurogastroenterology and Motility

|July 2, 2020

Summary

This summary is machine-generated.

A new wireless gastric electrical stimulation (GES) device was successfully implanted endoscopically in pigs. This minimally invasive approach shows promise for treating gastroparesis, potentially increasing GES utilization.

Keywords:

Electric stimulation Endoscopy Gastroparesis

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Area of Science:

Gastroenterology
Biomedical Engineering
Medical Devices

Background:

Gastric electrical stimulation (GES) is a treatment for gastroparesis.
Current GES devices require invasive surgery and repeat procedures.
A need exists for less invasive GES delivery methods.

Purpose of the Study:

To develop a wireless, miniature GES device.
To test the feasibility of endoscopic insertion of this device in an animal model.

Main Methods:

The wireless GES device was implanted endoscopically into a submucosal pocket in pigs.
Gastric myoelectrical activity was recorded using an electrogastrogram.
Gastric slow waves were measured during electrical stimulation.

Main Results:

Gastric electrical stimulation (GES) resulted in more consistent gastric slow waves.
The frequency-to-amplitude ratio of gastric activity was significantly altered by GES.
The wireless device was successfully implanted endoscopically.

Conclusions:

Minimally invasive wireless GES is feasible.
This technology may enhance the adoption of GES for gastroparesis treatment.