Stress-Induced Takotsubo Cardiomyopathy After Transjugular Intrahepatic Portosystemic Shunt

Bernadette Lamb1, Benjamin Arbeiter1, Neil Bhogal2

  • 1Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE.

Insights

This case report details Takotsubo cardiomyopathy, a form of heart failure, following a transjugular intrahepatic portosystemic shunt procedure. The patient recovered fully with medical treatment, highlighting a potential complication of the procedure.

Area of Science:

  • Cardiology
  • Hepatology
  • Interventional Radiology

Background:

  • Transjugular intrahepatic portosystemic shunt (TIPS) procedures are common for managing complications of portal hypertension.
  • Cirrhotic cardiomyopathy is a known complication in patients with advanced liver disease.
  • Takotsubo cardiomyopathy, or stress-induced cardiomyopathy, is typically associated with emotional or physical stress.

Observation:

  • A 59-year-old woman with decompensated cirrhosis developed new-onset heart failure post-TIPS.
  • The patient had no prior history of cardiovascular disease or cirrhotic cardiomyopathy.
  • Echocardiography revealed transient left ventricular systolic dysfunction.

Findings:

  • This is the first documented case of Takotsubo cardiomyopathy occurring after a TIPS procedure.
  • The patient's heart function recovered within two weeks of medical management.
  • Treatment involved beta-blockers and diuretics.

Implications:

  • Takotsubo cardiomyopathy should be considered in patients presenting with new-onset heart failure after TIPS.
  • Further research is needed to understand the mechanism linking TIPS and Takotsubo cardiomyopathy.
  • This case highlights the importance of comprehensive cardiovascular monitoring in patients undergoing TIPS.

Related Concept Videos

Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
311
Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
328
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
281
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
252
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
568
Cardiomyopathy VI: Nursing Management01:29

Cardiomyopathy VI: Nursing Management

Assessment: Nursing management of patients with cardiomyopathy begins with a thorough assessment of the patient's history, including a family history of cardiomyopathy or sudden cardiac death, personal history of heart disease, hypertension, diabetes, and any alcohol consumption or drug use.During the physical examination, assess vital signs, look for signs of heart failure (such as edema, jugular venous distention, and cyanosis), auscultate for abnormal heart sounds (like murmurs and gallops),...
212