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Determining the Functional Status of the Corticospinal Tract Within One Week of Stroke
Published on: February 22, 2020
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Different predictors after stroke depending on functional dependency at discharge: a 5-year follow up study
Emma Westerlind1, Daniel Hörsell1, Hanna C Persson2
1Institute of Neuroscience and Physiology, Department of Clinical Neuroscience, Sahlgrenska Academy, Sahlgrenska University Hospital, Per Dubbsgatan 14, 413 45, Gothenburg, Sweden.
BMC Neurology
|July 3, 2020
Summary
Predictors of stroke outcome differ by functional dependency. Modifiable factors like depression and cardiovascular risks impact outcomes for dependent individuals, offering targets for intervention.
Area of Science:
- Neurology
- Rehabilitation Medicine
- Public Health
Background:
- Functional dependency post-stroke significantly impacts long-term outcomes.
- Predictors of stroke outcome vary based on initial functional dependency levels.
- Understanding these predictors is crucial for targeted rehabilitation strategies.
Purpose of the Study:
- To investigate self-perceived outcomes 5 years post-stroke.
- To identify predictors of strength, participation, and emotional well-being.
- To differentiate predictors based on functional dependency at hospital discharge.
Main Methods:
- Observational cohort study of first-ever stroke patients (2009-2010).
- Data collected from medical charts and the Stroke Impact Scale (SIS) at 5-year follow-up.
- Logistic regression analysis to identify outcome predictors.
Main Results:
- Functionally independent patients reported better outcomes across all SIS domains.
- For independent patients, non-modifiable factors (age, sex, stroke type) predicted outcomes.
- For dependent patients, modifiable factors (depression, cardiovascular risks, recurrent stroke) predicted unfavorable outcomes.
Conclusions:
- Predictors of favorable stroke outcomes are dependent on functional status at discharge.
- Modifiable factors significantly influenced outcomes in functionally dependent stroke survivors.
- Targeting modifiable factors in dependent individuals can improve long-term stroke recovery and reduce burden.

