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Intraocular extraskeletal osteosarcoma in a rabbit (Oryctolagus cuniculus).
Risa Makishima1, Hirotaka Kondo1, Atsuto Naruke2
1Laboratory of Veterinary Pathology, Department of Veterinary Medicine, Nihon University, Fujisawa, Kanagawa 252-0813, Japan.
A rabbit presented with an enlarged eye due to osteosarcoma, a rare intraocular neoplasm. This case marks the first documented instance of intraocular osteosarcoma in a rabbit.
Area of Science:
- Veterinary Pathology
- Oncology
- Ophthalmology
Background:
- Intraocular neoplasms are infrequently reported in pet rabbits (Oryctolagus cuniculus).
- Osteosarcoma is a malignant bone tumor rarely found in the eye.
Observation:
- An 8-year-and-9-month-old male lop-eared rabbit exhibited progressive left eye enlargement and exophthalmos.
- Gross necropsy revealed a hard, light-gray mass effacing intraocular tissues.
Findings:
- Histological examination confirmed the mass as osteosarcoma, characterized by spindle to angular cells producing osteoid, bone, and cartilage.
- The tumor occluded the intraocular structures.
Implications:
- This case represents the first pathological documentation of intraocular osteosarcoma in a rabbit.
- Highlights the importance of considering rare neoplasms in rabbit ophthalmology.
- Contributes to the limited literature on rabbit intraocular tumors.
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