Massive Pulmonary Thromboembolism in Patients with COVID-19; Report of Three Cases

Mehdi Pishgahi1, Zahra Ansari Aval2, Behzad Hajimoradi3

  • 1Cardiology Department, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Insights

Severe COVID-19 cases can lead to pulmonary thromboembolism (PTE). Early anticoagulant prophylaxis with low-molecular-weight heparin (LMWH) is recommended for intensive care unit (ICU) patients to improve outcomes.

Area of Science:

  • Critical Care Medicine
  • Infectious Diseases
  • Cardiology

Background:

  • COVID-19 presents diverse clinical manifestations, with coagulopathies and thromboembolic events increasingly recognized as critical factors.
  • Understanding the link between severe COVID-19 and thrombotic complications is crucial for patient management.

Observation:

  • Three intensive care unit (ICU) patients with severe COVID-19 developed massive pulmonary thromboembolism (PTE) shortly after disease onset.
  • One patient experienced a fatal outcome, while two were successfully treated with thrombectomy and antithrombotic agents, respectively.

Findings:

  • Severe COVID-19 is associated with a significant risk of developing massive pulmonary thromboembolism (PTE).
  • Prompt medical intervention, including thrombectomy and antithrombotic therapy, can be effective in managing PTE in COVID-19 patients.

Implications:

  • Physicians should proactively consider and plan for anticoagulant prophylaxis, particularly using low-molecular-weight heparin (LMWH), in severe COVID-19 cases.
  • Early recognition and management of PTE are essential for improving prognosis in critically ill COVID-19 patients.

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