Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Physical Methods for Controlling Microbial Growth: Temperature01:23

Physical Methods for Controlling Microbial Growth: Temperature

817
Heat is a widely used method to control microbial growth by targeting and denaturing cellular proteins, thereby killing or inactivating microbes. This method's effectiveness is quantified using parameters such as the thermal death point (TDP), thermal death time (TDT), and decimal reduction time (D value). TDP represents the lowest temperature at which all microorganisms in a liquid suspension are eliminated within 10 minutes, whereas TDT is the time necessary to achieve sterilization at a...
817
Methods of Sterilization I: Physical Methods01:29

Methods of Sterilization I: Physical Methods

23.2K
As used in a healthcare facility, sterilization destroys all microorganisms through physical or chemical methods. The physical method includes steam, dry heat, boiling water, and radiation.
Steam sterilization uses non-toxic, low-cost moist heat in the form of saturated steam under pressure, which is fast, microbicidal, and sporicidal, and quickly warms and penetrates fabrics. Autoclaves, or steam sterilizers, expose each item to direct steam contact for a predetermined time at the necessary...
23.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Improved closure of the global mean sea level budget from observational advances since 1960.

Science advances·2026
Same author

Integrated chromatin and transcriptomic profiling reveals sex-specific mechanisms of gene regulation in hepatic nutrient responses.

PLoS biology·2026
Same author

Oceanic memory of tropical cyclones moderates the Kuroshio current.

Nature communications·2025
Same author

A genome-wide ATLAS of liver chromatin accessibility reveals that sex dictates diet-induced nucleosome dynamics.

bioRxiv : the preprint server for biology·2025
Same author

Enhanced ocean heat storage efficiency during the last deglaciation.

Science advances·2024
Same author

Retraction notice to "Dencichine ameliorates renal injury by improving oxidative stress, apoptosis and fibrosis in diabetic rats" [Life Sci. 258 (2020) 118146].

Life sciences·2024
Same journal

From Norovirus to Andes Hantavirus: Indirect Viral Transmission and Emerging Prevention Strategies for Cruise Ship and Confined Environments.

Reviews in medical virology·2026
Same journal

Matrix Metalloproteinases and Viral Hepatitis: A Complex Interplay Driving Liver Fibrosis, Immune Dysregulation, and Hepatocarcinogenesis.

Reviews in medical virology·2026
Same journal

Kyasanur Forest Disease: Advances in Experimental Animal Models, Immune Assays, and Challenges in Vaccine Development.

Reviews in medical virology·2026
Same journal

A Cross-Country Evaluation of Respiratory Syncytial Virus and Human Metapneumovirus Surveillance Systems: Identifying Gaps and Best Practices for Improved Disease Monitoring.

Reviews in medical virology·2026
Same journal

The Global Health Security Challenges Posed by Recurring Nipah Virus Outbreaks.

Reviews in medical virology·2026
Same journal

Immunological Interactions Between Gammadelta T Cells and West Nile Virus in the Infected Host.

Reviews in medical virology·2026
See all related articles

Related Experiment Video

Updated: Dec 16, 2025

A Tuberculosis Molecular Bacterial Load Assay TB-MBLA
10:41

A Tuberculosis Molecular Bacterial Load Assay TB-MBLA

Published on: April 30, 2020

14.6K

Using heat to kill SARS-CoV-2.

John P Abraham1, Brian D Plourde1, Lijing Cheng2

  • 1School of Engineering, University of St. Thomas, St. Paul, Minnesota, USA.

Reviews in Medical Virology
|July 3, 2020
PubMed
Summary
This summary is machine-generated.

Thermal inactivation of SARS-CoV-2, the virus causing COVID-19, is crucial for sterilization. This review outlines temperatures and exposure times needed for inactivation, comparing them to household appliance capabilities.

More Related Videos

Determining Viral Disinfection Efficacy of Hot Water Laundering
06:57

Determining Viral Disinfection Efficacy of Hot Water Laundering

Published on: June 21, 2022

2.9K
Protocol for Recombinant RBD-based SARS Vaccines: Protein Preparation, Animal Vaccination and Neutralization Detection
12:09

Protocol for Recombinant RBD-based SARS Vaccines: Protein Preparation, Animal Vaccination and Neutralization Detection

Published on: May 2, 2011

43.3K

Related Experiment Videos

Last Updated: Dec 16, 2025

A Tuberculosis Molecular Bacterial Load Assay TB-MBLA
10:41

A Tuberculosis Molecular Bacterial Load Assay TB-MBLA

Published on: April 30, 2020

14.6K
Determining Viral Disinfection Efficacy of Hot Water Laundering
06:57

Determining Viral Disinfection Efficacy of Hot Water Laundering

Published on: June 21, 2022

2.9K
Protocol for Recombinant RBD-based SARS Vaccines: Protein Preparation, Animal Vaccination and Neutralization Detection
12:09

Protocol for Recombinant RBD-based SARS Vaccines: Protein Preparation, Animal Vaccination and Neutralization Detection

Published on: May 2, 2011

43.3K

Area of Science:

  • Virology
  • Infectious Diseases
  • Public Health

Background:

  • The global coronavirus pandemic (COVID-19) necessitates effective sterilization methods for contaminated objects.
  • Controlling the spread of SARS-CoV-2 requires understanding its inactivation parameters.

Purpose of the Study:

  • To review existing literature on the thermal inactivation of SARS-CoV-2.
  • To provide preliminary guidelines for temperatures and exposure durations for sterilization.
  • To compare effective thermal inactivation parameters with the capabilities of common household appliances.

Main Methods:

  • Literature review of studies on thermal inactivation of coronaviruses, specifically SARS-CoV-2.
  • Analysis of temperature and time data for viral inactivation.
  • Comparison of identified thermal parameters with specifications of household appliances.

Main Results:

  • Identification of specific temperature ranges and exposure durations effective for SARS-CoV-2 thermal inactivation.
  • Preliminary guidelines for thermal sterilization of SARS-CoV-2 are presented.
  • Assessment of the potential of household appliances to achieve these sterilization parameters.

Conclusions:

  • Thermal inactivation is a viable method for SARS-CoV-2 sterilization.
  • Understanding precise temperature and time requirements is essential for effective decontamination.
  • Further research is needed to validate the efficacy of household appliances for SARS-CoV-2 sterilization.