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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
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Sarcoidosis presenting as hiccups.

Melissa Neumann1, Kevin G Lazo2, Diane Stover2

  • 1Department of Medicine Northwell Health Manhasset NY USA.

Respirology Case Reports
|July 4, 2020
PubMed
Summary

Persistent hiccups can rarely be caused by sarcoidosis. This case report highlights thoracic sarcoidosis as a potential cause, reviewing mechanisms and treatments for this uncommon condition.

Keywords:
Chronic hiccupshiccupspersistent hiccupssarcoidosis

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Area of Science:

  • Pulmonology
  • Neurology

Background:

  • Hiccups are a common, often benign, symptom.
  • Sarcoidosis is an inflammatory disease that can affect multiple organs.
  • Hiccups due to sarcoidosis are rarely reported.

Observation:

  • A case of persistent hiccups possibly caused by hilar/mediastinal lymph node enlargement due to sarcoidosis is presented.
  • A literature search identified eight case reports of hiccups related to sarcoidosis.
  • Only one prior case linked hiccups to thoracic lymphadenopathy from sarcoidosis; most cases involved central nervous system sarcoidosis.

Findings:

  • Thoracic sarcoidosis, specifically lymph node enlargement, is identified as a potential cause of persistent hiccups.
  • The underlying mechanisms of hiccups are reviewed.
  • Co-morbid conditions associated with hiccups, including sarcoidosis, are explored.

Implications:

  • This case expands the understanding of potential causes for persistent hiccups.
  • It suggests thoracic sarcoidosis should be considered in the differential diagnosis of unexplained persistent hiccups.
  • Further research into effective management strategies for sarcoidosis-induced hiccups is warranted.