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Fatal Superimposed Bacterial Sepsis in a Healthy Coronavirus (COVID-19) Patient
1Internal Medicine, Saint Peter's University Hospital, New Brunswick, USA.
Insights
A healthy individual with COVID-19 rapidly deteriorated due to a secondary bacterial infection. Early procalcitonin testing may help identify fatal bacterial infections in COVID-19 patients.
Area of Science:
- Infectious Diseases
- Critical Care Medicine
Background:
- Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, is a global pandemic.
- Transmission occurs via respiratory droplets and environmental contamination, necessitating social distancing.
- Individuals with comorbidities face higher risks of severe complications like ARDS.
Observation:
- A case report details a healthy COVID-19 patient with no comorbidities who experienced rapid deterioration.
- The patient succumbed to the disease following a superimposed bacterial infection complicating COVID-19 pneumonia.
Findings:
- Healthy individuals may experience mild illness or be asymptomatic.
- Superimposed bacterial infections can lead to fatal outcomes even in previously healthy COVID-19 patients.
Implications:
- Educating COVID-19 patients on precautions and signs of secondary bacterial infection is crucial for home care.
- Routine procalcitonin level checks at initial presentation could aid in ruling out fatal bacterial infections in COVID-19 cases.
Abstract:
Coronavirus disease 2019 (COVID-19) is a highly infectious disease caused by the newly discovered coronavirus, SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2). The novel coronavirus first emerged in Wuhan, China, in December 2019 and has led to a global pandemic. The virus mainly spreads through respiratory droplets from an infected person, but environmental contamination can also act as a source of infection, making social distancing an important key in containing the spread of infection. Those with underlying health conditions are more susceptible to complications such as acute respiratory distress syndrome, which can be fatal. However, healthy individuals experience a mild flu-like illness or may be asymptomatic, recuperating from the infection even without any particular intervention. We present a case of a healthy COVID positive individual, with no underlying comorbidities, who rapidly deteriorated overnight on readmission to the hospital after initial discharge and succumbed to this disease due to a superimposed bacterial infection with COVID pneumonia. This case report highlights the importance of educating COVID-19 positive patients about the precautions, as well as signs and symptoms of a superimposed bacterial infection, when their plan of care is in a home setting. It also emphasizes the potential role of checking procalcitonin levels as a part of routine laboratory investigation at initial presentation in all suspected as well as confirmed COVID-19 cases to rule out an on-going bacterial infection that can prove fatal in the course of the disease.
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