Fatal Superimposed Bacterial Sepsis in a Healthy Coronavirus (COVID-19) Patient

Merin Jose1, Krishna Desai2

  • 1Internal Medicine, Saint Peter's University Hospital, New Brunswick, USA.

Cureus
|July 4, 2020
PubMed

Insights

A healthy individual with COVID-19 rapidly deteriorated due to a secondary bacterial infection. Early procalcitonin testing may help identify fatal bacterial infections in COVID-19 patients.

Area of Science:

  • Infectious Diseases
  • Critical Care Medicine

Background:

  • Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, is a global pandemic.
  • Transmission occurs via respiratory droplets and environmental contamination, necessitating social distancing.
  • Individuals with comorbidities face higher risks of severe complications like ARDS.

Observation:

  • A case report details a healthy COVID-19 patient with no comorbidities who experienced rapid deterioration.
  • The patient succumbed to the disease following a superimposed bacterial infection complicating COVID-19 pneumonia.

Findings:

  • Healthy individuals may experience mild illness or be asymptomatic.
  • Superimposed bacterial infections can lead to fatal outcomes even in previously healthy COVID-19 patients.

Implications:

  • Educating COVID-19 patients on precautions and signs of secondary bacterial infection is crucial for home care.
  • Routine procalcitonin level checks at initial presentation could aid in ruling out fatal bacterial infections in COVID-19 cases.

Related Concept Videos

Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

The pathophysiology of pneumonia involves the following steps:
2.3K
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
5.2K
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
684
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
257
Acute Respiratory Failure-II01:21

Acute Respiratory Failure-II

Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
876
Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
282