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Delineating anatomy and function with multimodality imaging: a case report of giant right coronary artery aneurysms
Kameel Kassab1, Mina Iskander1, Saurabh Malhotra1
1Division of Cardiology, Department of Cardiology, John H. Stroger, Jr. Hospital of Cook County, 1901 W. Harrison Street, Room 3620, Chicago, IL 60612, USA.
Insights
Giant coronary artery aneurysms (CAAs) are rare. Multimodality imaging, including CT angiography and MRI, is crucial for diagnosing these aneurysms and assessing their impact on heart function.
Area of Science:
- Cardiology
- Radiology
- Medical Imaging
Background:
- Giant coronary artery aneurysms (CAAs) are rare cardiovascular conditions.
- Associated with connective tissue diseases, arteritides, and atherosclerosis.
- Multimodality imaging is vital for evaluation and hemodynamic assessment.
Observation:
- A 58-year-old female presented with exertional dyspnea.
- Computed tomography (CT) revealed right coronary artery (RCA) aneurysms.
- Invasive coronary angiogram (ICA) confirmed two giant RCA aneurysms.
Findings:
- Coronary CT angiography (CCTA) identified an additional distal RCA aneurysm with thrombosis.
- Contrast-enhanced cardiac magnetic resonance imaging (CMR) showed reduced inferior wall perfusion.
- CMR also revealed aneurysmal wall inflammation.
Implications:
- Multimodality imaging accurately characterizes giant CAAs, including extent and thrombosis.
- Reduced perfusion likely caused exertional symptoms.
- Surgical resection with bypass grafting is the recommended management.
Background:
Giant coronary artery aneurysms (CAAs) are rare and have been reported in patients with connective tissue diseases, arteritides, and atherosclerosis. Given the rarity of the condition, multimodality imaging is essential for comprehensive evaluation of coronary aneurysms and determination of their haemodynamic significance.
Case Summary:
A 58-year-old Filipino female was evaluated for dyspnoea on exertion of one month. Chest computed tomography (CT) showed right coronary artery (RCA) aneurysms. Invasive coronary angiogram (ICA) confirmed two giant aneurysms of the RCA. Distal RCA could not be opacified due to contrast stagnation in the proximal aneurysms. Coronary CT angiography (CCTA) depicted an additional giant distal RCA aneurysm not visualized on ICA with intraluminal thrombosis. Contrast-enhanced cardiac magnetic resonance imaging (CMR) revealed delayed time to peak perfusion in the mid to apical inferior walls, on first-pass imaging, without myocardial scarring. Late gadolinium images revealed aneurysmal wall inflammation.
Discussion:
This case highlights the anatomical findings of giant CAA and the application of multimodality imaging for their accurate characterization. While ICA confirmed the presence of the aneurysms, CCTA enabled the assessment of their full extent and depict intraluminal thrombosis. Contrast-enhanced CMR delineated aneurysm wall characteristics, with first-pass images demonstrating reduced inferior wall perfusion at rest, which was likely the cause of patient's exertional symptoms. Management of giant coronary aneurysms involves surgical resection with bypass grafting.
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