Related Experiment Video
Updated: Dec 16, 2025

Germ Cell Transplantation and Testis Tissue Xenografting in Mice
Published on: February 6, 2012
Testicular transposition in children before scrotal external radiotherapy
Marielle Le Bon1, Herve Lejeune2, Sylvie Helfre3
1Radiation Oncology Department, Centre Léon Bérard, Lyon, France.
Abstract:
Testicular transposition (TT) before scrotal external radiotherapy (RT) is poorly reported in children with cancer, with only rare case reports published. TT surgical techniques, dosimetric parameters, and testicular functions are retrospectively reported in 12 children, median age 12.8 years, after scrotal RT for sarcomas. TT has low morbidity and allows a dramatic RT dose decrease in the healthy testicle. Endocrine functions seem preserved while more follow-up is needed to assess fertility. Though a rare situation, TT should be discussed in children and young adult cases when a scrotal high-dose RT is needed.

