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Updated: Dec 16, 2025

Mizoroki-Heck Cross-coupling Reactions Catalyzed by Dichloro{bis[1,1',1''-phosphinetriyltripiperidine]}palladium Under Mild Reaction Conditions
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Mizoroki-Heck Cross-coupling Reactions Catalyzed by Dichloro{bis[1,1',1''-phosphinetriyltripiperidine]}palladium Under Mild Reaction Conditions

Published on: March 20, 2014

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Utilizing Vinylcyclopropane Reactivity: Palladium-Catalyzed Asymmetric [5+2] Dipolar Cycloadditions

Miao-Miao Li1, Qin Xiong2, Bao-Le Qu1

  • 1CCNU-uOttawa Joint Research Centre, Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, 152 Luoyu Road, Wuhan, Hubei, 430079, China.

Angewandte Chemie (International Ed. in English)
|July 4, 2020
PubMed
Summary

This study introduces a new palladium-catalyzed reaction using vinylcyclopropanes (VCPs) and α-diazoketones to create enantioenriched seven-membered lactones. This visible-light-driven method offers high efficiency and selectivity in modern synthetic chemistry.

Keywords:
asymmetric catalysiscycloadditionketenesmedium-sized ringspalladium

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