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Updated: Dec 16, 2025

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
Published on: March 24, 2023
Pediatric contact dermatitis: what's new
Insights
Allergic contact dermatitis (ACD) is increasingly common in children, often requiring patch testing for diagnosis. Management focuses on identifying and avoiding specific allergens like nickel and fragrances.
Area of Science:
- Pediatric Dermatology
- Allergy and Immunology
Background:
- Allergic contact dermatitis (ACD) is increasingly recognized in children, contrary to previous beliefs of its rarity.
- Factors such as changing trends in toys, hobbies, and personal care products may contribute to rising ACD prevalence in pediatric populations.
Purpose of the Study:
- To review the current understanding of allergic contact dermatitis (ACD) in children.
- To highlight diagnostic approaches and common allergens implicated in pediatric ACD.
Main Methods:
- Review of recent studies and patch testing data in pediatric populations.
- Discussion of clinical features differentiating ACD from atopic dermatitis.
- Reference to the 2018 expert consensus-derived pediatric baseline series for patch testing.
Main Results:
- Nickel, cobalt, neomycin, balsam of Peru, fragrance mixes I and II, methylisothiazolinone, formaldehyde, and lanolin are frequently identified allergens in children with ACD.
- Patch testing is becoming more common for diagnosing ACD in children.
- ACD can coexist with atopic dermatitis, necessitating careful clinical evaluation.
Conclusions:
- Allergic contact dermatitis (ACD) is a significant and growing concern in pediatric dermatology.
- Accurate diagnosis via patch testing and diligent allergen avoidance are crucial for managing pediatric ACD.
- Understanding common pediatric allergens is key to effective prevention and treatment strategies.
Purpose Of Review:
Allergic contact dermatitis (ACD) was once thought to be rare in children but recent studies have demonstrated that the prevalence of ACD is common and appears to be increasing in children. Current trends including toys, hobbies, and personal care products may play a role in potentially new allergen exposure or resurgence of certain allergens, making ACD a moving target in children.
Recent Findings:
ACD and atopic dermatitis can coexist and certain clinical features can help differentiate ACD from endogenous atopic dermatitis in children. It is important to consider ACD in children with recalcitrant atopic dermatitis or dermatitis with atypical distribution. Patch testing has become a more common practice in children. In 2018, the first expert consensus-derived pediatric baseline series consisting of 38 allergens was proposed to aid in the diagnosis of ACD in children. Comparing recent patch testing data in the pediatric population, the top allergens ubiquitously identified were nickel, cobalt, neomycin, Myroxylon pereirae (balsam of Peru), fragrance mix I, fragrance mix II, methylisothiazolinone, methylchloroisothiazolinone/ methylisothiazolinone, formaldehyde, and lanolin.
Summary:
ACD is a common problem in children. Detection through patch testing, avoidance of offending allergens, and prevention of common allergens are the main focus of management of ACD in children.
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