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Risk factors for the recurrence of convulsions with mild gastroenteritis in children
Kaili Shi1, Jiehui Yang2, Yunhong Wu3
1Department of Neurology, Guangzhou Women and Children's Medical Center, Guangzhou, China; Department of Neurology, Children's Hospital of Shanxi Province, Taiyuan, China.
Insights
Recurrence of convulsions with mild gastroenteritis (CwG) is possible, especially within 6 months. Key risk factors include onset before 18 months and family history of seizures, necessitating close follow-up.
Area of Science:
- Pediatrics
- Neurology
- Infectious Diseases
Background:
- Convulsions with mild gastroenteritis (CwG) are a common pediatric concern.
- Understanding recurrence patterns is crucial for effective management.
Purpose of the Study:
- To identify risk factors for the recurrence of convulsions with mild gastroenteritis (CwG) in children.
- To inform clinical observation and follow-up strategies for CwG.
Main Methods:
- Retrospective analysis of clinical data from 613 children diagnosed with CwG.
- Longitudinal follow-up of patients for 4-10 years to assess recurrence.
- Statistical analysis to identify significant risk factors for CwG recurrence.
Main Results:
- A recurrence rate of 6.3% was observed in the study cohort.
- Most recurrences (80%) occurred within 6 months of the initial episode.
- Significant risk factors for CwG recurrence included age at first attack ≤18 months and a family history of convulsions in first-degree relatives.
Conclusions:
- Children experiencing CwG have a notable risk of recurrence, particularly within the first six months.
- Early age of onset (≤18 months) and a familial history of seizures are identified as significant predictors of CwG recurrence.
- Close monitoring and follow-up are recommended for children with these risk factors.
Purpose:
To identify risk factors for the recurrence of convulsions with mild gastroenteritis (CwG)1 in children.
Methods:
Altogether, 613 children with CwG admitted to Children's Hospital of Shanxi Province from January 2010 to December 2015 were selected, their clinical data were retrospectively analyzed, and patients were followed up for 4-10 years. Risk factors for the recurrence of CwG were analyzed based on the clinical characteristics of the children.
Results:
Relapse occurred in 35 patients (6.3 %). Recurrence occurred within 6 months after the first CwG in majority of the patients (80 %), and recurrence occurred once in most patients (91.4 %). Risk factors associated with CwG recurrence were age at first attack of ≤18 months (recurrence rates at ages ≤ and >18 months were 8.7 %, and 3.1 %, respectively; χ2 = 4.856, P = 0.028), and a history of convulsions in first-degree relatives (recurrence rates in first-degree relatives with and without a history of convulsion were 20 % and 6.2 %, respectively; χ2 = 5.501, P = 0.019).
Conclusions:
Children with CwG have a possibility of recurrence. The risk of recurrence within 6 months of onset is high and such patients should be carefully observed. Furthermore, the age of onset of ≤18 months and history of convulsions in first-degree relatives are risks factors for CwG recurrence; therefore, these children should be closely followed up.
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