[Features of cerebral venous hemodynamic in patients with hypertensive encephalopathy]

To study the characteristics of main clinical and diagnostic indicators of cerebral venous circulation and their dynamics in patients with hypertensive encephalopathy of various stages treated with cytoflavin.

Clinical and instrumental data of the examination of 105 patients with the established diagnosis of hypertensive encephalopathy of various stages were analyzed. Cerebral hemodynamics was investigated using transcranial duplex scanning of the veins and sinuses of the brain. Patients (n=85) with diagnostic signs of cerebral venous dysfunction were stratified into two groups by treatment regimen: main group (n=39) received standard antihypertensive therapy with cytoflavin (2 tablets 2 times a day from 1 to 30 days), the control group (n=46) received standard treatment. Control studies of cerebral hemodynamics were performed in both groups on the 30th and 60th day from the start of therapy.

Conclusion. The patients who received cytoflavin in the treatment regimen showed a slight improvement on the 30th day and a significant improvement in venous cerebral circulation indicators on the 60th day (p<0,05), which made it possible to conclude that the drug is effective for improving cerebral venous hemodynamics, and to recommend it in the complex therapy of patients with hypertensive encephalopathy of various stages with existing venous cerebral disorders.