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Lymphoid Cells and Tissues01:18

Lymphoid Cells and Tissues

2.6K
Lymphoid cells and tissues are integral to the immune system, which is crucial in maintaining our body's defense against harmful pathogens. They form the building blocks of lymphoid organs, which include the spleen, thymus, and lymph nodes.
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
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Detailed Structure and Function of Lymph Nodes01:23

Detailed Structure and Function of Lymph Nodes

3.9K
Lymph nodes are bean-shaped structures that cluster along the lymphatic vessels in the inguinal, axillary, and cervical regions. Each node is divided into compartments by a capsule that extends trabeculae inward.
From a histological perspective, lymph nodes can be split into two main areas: the superficial cortex and the deep medulla. The outer cortex is populated by dendritic cells, macrophages, and B lymphocytes, which are densely packed into follicles. When these B-lymphocytes are presented...
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Secondary Lymphoid Organs01:15

Secondary Lymphoid Organs

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Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
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Lymphatic Vessels and Lymph Transport01:16

Lymphatic Vessels and Lymph Transport

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Lymphatic vessels, known as lymphatics, are crucial in transporting lymph from peripheral tissues to our venous system. This process begins with lymph entering through tiny capillaries that branch through tissues. These capillaries have unique features such as larger diameters, thinner walls, and a distinctive one-way valve system formed by overlapping endothelial cells.
This one-way system allows fluids, solutes, and even pathogens to enter but prevents their return to the intercellular...
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Related Experiment Video

Updated: Dec 16, 2025

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
07:36

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Published on: May 1, 2015

14.8K

Pseudolymphomatous folliculitis.

Belinda Roque Quintana1, Yeray Peñate, Társila Montenegro Dámaso

  • 1Department of Dermatology, Complejo Hospitalario Universitario Insular-Materno Infantil, Las Palmas de Gran Canaria. Belinda.rq@hotmail.com.

Dermatology Online Journal
|July 5, 2020
PubMed
Summary

Pseudolymphomatous folliculitis, a benign condition, requires differentiation from malignancies due to rapid growth. Dermatoscopic findings of follicular plugs on an erythematous base aid in diagnosis.

Area of Science:

  • Dermatology
  • Pathology

Background:

  • Pseudolymphomatous folliculitis is a rare benign condition within the spectrum of pseudolymphomas.
  • It presents diagnostic challenges due to rapid clinical growth and potentially suspicious histology, necessitating differentiation from malignant neoplasms.

Observation:

  • A middle-aged woman presented with a 6-month history of a facial erythematous plaque.
  • Dermatoscopy revealed characteristic follicular plugs on an erythematous base.

Findings:

  • Histopathology confirmed a dense lymphocytic infiltrate with folliculotropism and follicular alteration.
  • Peripheral histiocytes tested positive for S100 and CD1a markers.

Implications:

  • This case expands the understanding of dermatoscopic features associated with pseudolymphomatous folliculitis.

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  • Accurate diagnosis is crucial for appropriate management, distinguishing it from cutaneous lymphomas.