Related Experiment Video

Updated: Dec 16, 2025

O-Ring Aortic Banding Versus Traditional Transverse Aortic Constriction for Modeling Pressure Overload-Induced Cardiac Hypertrophy
09:24

O-Ring Aortic Banding Versus Traditional Transverse Aortic Constriction for Modeling Pressure Overload-Induced Cardiac Hypertrophy

Published on: October 6, 2022

4.1K

Aortic Coarctation

Yuli Y Kim1, Lauren Andrade1, Stephen C Cook2

  • 1Philadelphia Adult Congenital Heart Center, Perelman School of Medicine at the University of Pennsylvania, Penn Medicine and Children's Hospital of Philadelphia, Perelman Center for Advanced Medicine, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA.

Cardiology Clinics
|July 6, 2020
PubMed

Insights

Aortic coarctation, a thoracic aorta narrowing, presents vascular issues beyond obstruction. Lifelong surveillance is crucial for adults with this condition to manage risks like hypertension and heart complications.

Area of Science:

  • Cardiology
  • Vascular Biology
  • Medical Imaging

Background:

  • Aortic coarctation involves thoracic aorta narrowing and abnormal vascular properties, including stiffness.
  • Despite interventions, patients face risks of hypertension, aortic issues, and left ventricular dysfunction.

Purpose of the Study:

  • To review the etiology, pathophysiology, diagnosis, and management of adult aortic coarctation.
  • To emphasize multimodality imaging and lifelong surveillance for long-term complications.

Main Methods:

  • Literature review focusing on adult aortic coarctation.
  • Analysis of etiology, pathophysiology, diagnostic methods, and treatment options.
  • Emphasis on imaging characteristics and surveillance strategies.

Main Results:

  • Aortic coarctation is a complex aortopathy requiring comprehensive management.
  • Multimodality imaging is key for diagnosis and monitoring complications.
  • Lifelong surveillance is essential for identifying and managing long-term risks.

Conclusions:

  • Adult aortic coarctation management requires a multidisciplinary approach.
  • Early diagnosis and continuous monitoring improve patient outcomes.
  • Understanding the aortopathy aspect is critical for effective lifelong care.

Keywords:
AortaAortic coarctationAortopathyCongenital heart diseaseStent therapy

More Related Videos

A Modified Technique for Transverse Aortic Constriction in Mice04:52

A Modified Technique for Transverse Aortic Constriction in Mice

Published on: August 18, 2022

5.5K
Technique of Minimally Invasive Transverse Aortic Constriction in Mice for Induction of Left Ventricular Hypertrophy08:34

Technique of Minimally Invasive Transverse Aortic Constriction in Mice for Induction of Left Ventricular Hypertrophy

Published on: September 25, 2017

25.2K

Related Concept Videos

Aneurysm I: Introduction01:30

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
192
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
266
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
303
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
123
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
241
Thoracic Aorta01:15

Thoracic Aorta

The thoracic section of the aorta begins at the T5 vertebra and extends to the T12 level at the diaphragm, initially progressing through the mediastinum to the left of the spinal column. Throughout its course in the thoracic segment, the thoracic aorta emits various offshoots known collectively as visceral and parietal branches. The branches that predominantly supply blood to visceral organs are termed visceral branches and include bronchial, pericardial, esophageal, and mediastinal arteries,...
1.3K