Related Experiment Video
Updated: Dec 16, 2025
08:40
Chronic Salmonella Infection Induced Intestinal Fibrosis
Published on: September 22, 2019
7.4K
Rheumatic manifestations in inflammatory bowel disease
Annacarla Finucci1, Maria Chiara Ditto2, Simone Parisi2
1Unit of Rheumatology, Città della Salute e della Scienza, Turin, Italy - annacarla.finucci@gmail.com.
Minerva Gastroenterology
|July 7, 2020
Summary
Rheumatic manifestations are common in inflammatory bowel disease (IBD), impacting quality of life. Early diagnosis and a multidisciplinary approach are crucial for managing IBD-related arthritis and preventing joint damage.
Area of Science:
- Gastroenterology and Rheumatology
Background:
- Rheumatic conditions are the most common extra-intestinal manifestations (EIMs) in inflammatory bowel disease (IBD).
- IBD is linked to musculoskeletal issues like arthritis, pain, and metabolic bone disease (osteoporosis).
- These manifestations significantly reduce patients' quality of life.
Purpose of the Study:
- To highlight the importance of recognizing and managing rheumatic EIMs in IBD patients.
- To emphasize the role of diagnostic imaging in identifying IBD-related musculoskeletal issues.
- To advocate for a multidisciplinary approach for improved patient outcomes.
Main Methods:
- Review of current understanding of rheumatic manifestations in IBD.
- Discussion of the utility of imaging techniques (ultrasound, MRI, X-rays) for diagnosis.
- Overview of available therapeutic options for IBD-related arthritides.
Main Results:
- Rheumatic EIMs are frequent and reduce quality of life in IBD patients.
- Various imaging modalities aid in diagnosing musculoskeletal manifestations.
- Effective treatments exist for both articular and intestinal aspects of IBD-related arthritis.
Conclusions:
- A multidisciplinary approach ensures early diagnosis and better clinical outcomes for IBD patients with rheumatic manifestations.
- Early intervention in IBD-related arthritis is key to controlling disease activity and preventing structural damage.
More Related Videos
Related Concept Videos
01:30Inflammatory Bowel Disease II: Crohn's Disease
792
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
792
01:27Inflammatory Bowel Disease I: Ulcerative Colitis
735
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
735
01:22Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
310
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
310
01:17Chronic Bowel Disorders: Introduction
678
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
678
01:23Rheumatic Heart Disease I: Introduction
297
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
297
01:24Drugs for Treatment of Crohn's Disease in IBD Using Biologic Agents: Anti-TNF
353
Tumor Necrosis Factor (TNF), a proinflammatory cytokine, contributes significantly to the inflammation seen in Crohn's disease. It exists as soluble TNF and membrane-bound TNF, with actions mediated through TNF receptors (TNFR). TNFR activation leads to the release of proinflammatory cytokines, T-cell activation, collagen production, and leukocyte migration, all contributing to inflammation in Crohn's disease. Anti-TNF monoclonal antibodies, namely infliximab (Remicade), adalimumab...
353