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Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists

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Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.

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Updated: Dec 16, 2025

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

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Published on: August 12, 2019

Preoperative cognitive screening tools

Jared A Herman¹, Ivan Urits², Alan D Kaye³

¹Mount Sinai Medical Center, Miami Beach, FL, United States of America.

Journal of Clinical Anesthesia

|July 7, 2020

Summary

No abstract available in PubMed .

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