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Updated: Dec 16, 2025

Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins
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Risk assessment of exotic disease incursion and spread.

, M Cabral1, R Taylor1

  • 1Animal and Plant Health Agency United Kingdom.

EFSA Journal. European Food Safety Authority
|July 7, 2020
PubMed
Summary
This summary is machine-generated.

This fellowship enhanced understanding of veterinary import risk assessment using diverse tools within the Generic Risk Assessment for Introduction of Animal Diseases (G-RAID) project. Practical application included assessing African swine fever and foot-and-mouth disease risks.

Keywords:
Import risk assessmentgeneric modelintroduction risklivestock diseasevalidation

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Area of Science:

  • Veterinary epidemiology
  • Quantitative risk assessment
  • Animal disease surveillance

Background:

  • The EU-FORA Fellowship focused on risk assessment (RA) for exotic animal disease incursion and spread.
  • Activities were centered within the Generic Risk Assessment for Introduction of Animal Diseases (G-RAID) project, integrating various European RA tools.

Purpose of the Study:

  • To deepen understanding of veterinary import risk assessment methodologies.
  • To explore the application of different algorithms in calculating disease incursion risks.
  • To gain insights into generic RA practices across Europe, including data uncertainty and reliability.

Main Methods:

  • Utilized a range of G-RAID RA tools, from qualitative to fully stochastic quantitative methods.
  • Conducted an inventory and quality assessment of publicly available databases for import RA.
  • Performed import risk assessments for African swine fever (using MINTRISK) and foot-and-mouth disease (using WBVR's RRAT and APHA's COMPARE models).

Main Results:

  • Gained comprehensive understanding of diverse RA algorithms and their application in risk estimation.
  • Identified and evaluated relevant databases for import RA, assessing their utility and limitations.
  • Successfully executed multiple import risk assessments, demonstrating proficiency with various RA tools.

Conclusions:

  • The fellowship provided valuable hands-on experience in quantitative risk assessment for animal diseases.
  • Enhanced ability to manage uncertainty and data variability in RA processes.
  • Strengthened professional network within the field of quantitative risk assessment.