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An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis
Published on: September 12, 2019
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Palliative care in hepatocellular carcinoma
Robyn Laube1, Abdul-Hamid Sabih2, Simone I Strasser2,3
1Department of Gastroenterology, Macquarie University Hospital, Sydney, New South Wales, Australia.
Journal of Gastroenterology and Hepatology
|July 7, 2020
Summary
Palliative care can improve quality of life for hepatocellular carcinoma patients but is underutilized. Improving integration and awareness can optimize end-of-life care for these patients.
Area of Science:
- Hepatology
- Oncology
- Palliative Medicine
Background:
- Hepatocellular carcinoma (HCC) presents a significant global health burden with poor prognosis.
- Patients often experience severe symptoms and discomfort during advanced stages or due to treatment side effects.
- Palliative care offers substantial benefits for quality of life and symptom management in end-stage liver disease.
Purpose of the Study:
- To highlight the underutilization of palliative care in hepatocellular carcinoma (HCC).
- To identify barriers to timely palliative care referrals in HCC.
- To propose strategies for improving palliative care integration and uptake in HCC.
Main Methods:
- Review of current literature on palliative care in HCC.
- Analysis of factors contributing to late referrals and underutilization.
- Discussion of potential models for integrating palliative and supportive care.
Main Results:
- Palliative care is underused in HCC despite proven benefits in other advanced cancers.
- Barriers include stigmatization, resource limitations, physician education gaps, and inadequate care models.
- Late referrals are common, limiting the potential benefits of palliative interventions.
Conclusions:
- Palliative care can significantly enhance the quality of life for HCC patients.
- Addressing barriers through education, awareness campaigns, and improved care models is crucial.
- Optimizing palliative care integration is essential for improving end-of-life care in HCC.
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