Donors after circulatory death heart trial

Area of Science:

• Cardiology
• Transplantation Surgery
• Medical Devices

Background:

• Orthotopic heart transplantation is the standard treatment for end-stage heart failure.
• A significant shortage of donor organs leads to long waitlists and delayed transplants.
• Extended criteria donors and donation after circulatory death (DCD) hearts offer potential to expand the donor pool.

Purpose of the Study:

• To evaluate the effectiveness of the Organ Care System (OCS) Heart System in preserving and assessing DCD hearts.
• To determine if the OCS Heart System can increase the availability of donor hearts for transplantation.
• To provide life-saving treatment to more patients with end-stage heart failure.

Main Methods:

• The study involves using the OCS Heart System to preserve and assess hearts from DCD donors.
• The trial aims to evaluate the viability and suitability of these preserved hearts for transplantation.
• Clinical trial registration: NCT03831048.

Main Results:

• This section is not yet available as the study is likely ongoing or results are pending.
• Further updates will be provided upon study completion and data analysis.

Conclusions:

• The OCS Heart System shows promise in expanding the donor heart pool by utilizing DCD organs.
• Successful implementation could significantly improve access to life-saving heart transplants for patients with end-stage heart failure.