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Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
Published on: June 10, 2025
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Hospital mortality in decompensated heart failure. A pilot study
Gianfranco Piccirillo1, Federica Moscucci1, Marco Valerio Mariani1
1Dipartimento di Scienze Cliniche, Internistiche, Anestesiologiche e Cardiovascolari, Policlinico Umberto I, "La Sapienza" University of Rome, Viale del Policlinico N. 155, 00185 Roma, Italy.
Journal of Electrocardiology
|July 7, 2020
Summary
Electrocardiogram (ECG) markers, specifically T peak to T end (Te) mean and standard deviation (SD), can identify patients with decompensated chronic heart failure (CHF) at high risk of in-hospital mortality. These noninvasive ECG measures offer promising predictive capabilities for patient outcomes.
Area of Science:
- Cardiology
- Medical Technology
- Biomedical Engineering
Background:
- Heart failure is a significant global cause of morbidity, mortality, and emergency department visits.
- Identifying high-risk decompensated chronic heart failure (CHF) patients is crucial for timely intervention.
Purpose of the Study:
- To identify electrocardiogram (ECG) markers for predicting in-hospital mortality in decompensated CHF patients.
- To investigate short-term temporal repolarization dispersion as a predictor of mortality risk.
Main Methods:
- Collected ECG data (RR, QTe, QTp, Te intervals) from decompensated CHF patients via mobile phone monitoring.
- Calculated mean, standard deviation (SD), and normalized index (N) for ECG variables.
- Utilized logistic multivariable and multiple regression analyses to identify mortality predictors.
Main Results:
- Deceased patients exhibited higher QTeSD, Te mean, TeSD, and QTeVN compared to survivors.
- Te mean was a significant predictor of in-hospital mortality (OR: 0.09; p=0.001).
- TeSD correlated positively with NT-pro BNP levels (r=0.540; p<0.001) and showed significant sensitivity/specificity for mortality.
Conclusions:
- Te mean and TeSD are promising noninvasive markers for identifying decompensated CHF patients at high risk of in-hospital mortality.
- These ECG-derived parameters offer a valuable tool for risk stratification in CHF management.
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