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Primary vaginal Ewing sarcoma with uterine fibroid: A case report
Medicine
|July 8, 2020
Summary
Primary vaginal Ewing sarcoma is a rare cancer. This case highlights successful surgical excision and chemotherapy for a patient with vaginal Ewing sarcoma and uterine fibroid, showing good recovery.
Area of Science:
- Oncology
- Gynecologic Oncology
- Sarcoma Research
Background:
- Extraosseous Ewing sarcoma (ES) is a rare malignancy, comprising approximately 15% of all Ewing sarcomas.
- ES commonly affects the paravertebral region, extremities, chest wall, retroperitoneum, pelvis, and hip.
- Primary vaginal Ewing sarcoma is exceptionally uncommon.
Observation:
- A 54-year-old woman presented with vaginal pain.
- Imaging revealed heterogeneous masses in the vagina and uterus.
- Biopsy confirmed a malignant tumor in the vaginal wall.
Findings:
- The patient underwent hysterectomy, bilateral salpingo-oophorectomy, and tumor excision.
- Adjuvant chemotherapy was administered post-surgery.
- The patient experienced a favorable outcome with no local recurrence for over a year.
Implications:
- This case underscores the rarity of primary vaginal Ewing sarcoma.
- Management involved a multimodal approach combining surgery and chemotherapy.
- Further research into optimal treatment strategies for vaginal ES is warranted.
