Prophylactic antibiotics for miscarriage surgery: A protocol for systematic review and meta-analysis

Area of Science:

• Medical research
• Infectious disease prevention
• Surgical safety

Background:

• Post-surgical infection is a significant risk following procedures to complete spontaneous abortions.
• While antibiotic prophylaxis is effective for some surgeries, its benefit for miscarriage surgery remains unproven.

Purpose of the Study:

• To systematically review the evidence on the effectiveness and safety of antibiotic prophylaxis in preventing infection during miscarriage surgery.
• To summarize current research findings to inform clinical decision-making.

Main Methods:

• A systematic review of randomized controlled trials from Cochrane, EMBASE, and PubMed databases (up to May 1, 2020).
• Independent study selection, data extraction, and quality assessment by two researchers.
• Statistical analysis using RevMan 5.3 software.

Main Results:

• This study will synthesize the latest evidence regarding the efficacy and safety of antibiotic prophylaxis for infection prevention in patients undergoing miscarriage surgery.
• A comprehensive summary of findings from relevant randomized controlled trials will be presented.

Conclusions:

• The findings are expected to offer guidance on the appropriate use of antibiotic prophylaxis for preventing infections after miscarriage surgery.
• This research aims to fill the current evidence gap and support evidence-based practice in women's healthcare.