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Updated: Jul 28, 2026

Retrograde Perfusion and Filling of Mouse Coronary Vasculature as Preparation for Micro Computed Tomography Imaging
Published on: February 10, 2012
Retrograde coronary sinus perfusion
H E Snyder1, W Smithwick, J T Wingard
1St. Vincent's Medical Center, Jacksonville, FL.
Abstract:
"Redo" operations for coronary artery disease have become commonplace. One of the major complications that occurs is perioperative infarction due to embolization of atheromatous material from diseased veins into the distal coronary arteries. Because of this, we began using retrograde coronary sinus perfusion (RCSP) for delivery of cardioplegia to prevent the embolization of grumous material. It is our belief that retrograde flow through the coronary arteries is an effective preventive measure. In addition, RCSP is a simple method of delivery in redo operations such as aortic valve replacement where the majority of coronary flow is through patent vein grafts. Sixty-five of approximately 3,100 patients in our practice in the past three years underwent a cardiac operation in which RCSP was used for cardioplegia delivery. Ventricular function in all patients was well preserved, and all survived. There were no complications associated with the use of this method.
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