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Updated: Dec 15, 2025

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Multiple nonmelanocytic skin cancers in multiple regions
Song Hyun Han1, Soon Heum Kim1, Cheol Keun Kim1
1Department of Plastic and Reconstructive Surgery, Konkuk University Chungju Hospital, Konkuk University School of Medicine, Chungju, Korea.
This case study highlights a 67-year-old man with multiple, asynchronous nonmelanocytic skin cancers (NMSC), including basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings emphasize the importance of vigilant monitoring and biopsy for patients with multiple NMSC diagnoses.
Area of Science:
- Dermatology
- Oncology
Background:
- Nonmelanocytic skin cancer (NMSC), comprising basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), is increasing globally.
- The Republic of Korea has observed a rise in skin cancer incidence, prompting greater scientific focus on NMSC.
Observation:
- A 67-year-old male patient presented with multiple, asynchronous NMSCs across various body sites.
- Initial diagnosis included BCC on the retro-auricle and SCC on the back and face.
- Further examination revealed additional BCC and SCC lesions on the neck, limbs, and head, along with supraglottic and external auditory canal SCC.
Findings:
- The patient was diagnosed with multiple BCC and SCC tumors, including rare locations like the external auditory canal.
- Surgical excision was performed for the primary SCC, with subsequent diagnoses of additional NMSCs.
Implications:
- Patients diagnosed with multiple NMSCs face a heightened risk of developing further skin cancers.
- Regular dermatological surveillance and prompt biopsy of suspicious lesions are crucial for managing patients with multiple NMSC diagnoses.
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