Related Experiment Video

Updated: Dec 15, 2025

Histological Quantification of Chronic Myocardial Infarct in Rats
09:45

Histological Quantification of Chronic Myocardial Infarct in Rats

Published on: December 11, 2016

15.2K

Myocardial blush grade: a determinant of left ventricular ejection fraction and adverse outcomes in STEMI

Adeel-Ur Rehman1, Jahanzeb Malik2, Nismat Javed3

  • 1Consultant Cardiologist, Department of Cardiology, Rawalpindi Institute of Cardiology, Pakistan.

Scottish Medical Journal
|July 8, 2020
PubMed

Insights

High myocardial blush grade predicts better outcomes after percutaneous intervention for ST-elevation myocardial infarction. This grading system is crucial for assessing ejection fraction improvement and reducing adverse events.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Cardiovascular Imaging

Background:

  • Microvascular obstruction can persist despite restored blood flow after percutaneous intervention.
  • Myocardial blush grade quantifies this subtle obstruction.
  • Assessing the impact of microvascular obstruction is vital for patient outcomes.

Purpose of the Study:

  • To investigate the relationship between myocardial blush grade and ejection fraction.
  • To determine the role of myocardial blush grade in predicting adverse outcomes post-intervention.
  • To evaluate myocardial blush grade as a predictor of recovery in ST-elevation myocardial infarction patients.

Main Methods:

  • Prospective, observational study design.
  • Data collection included demographics, ejection fraction, and myocardial blush grade.
  • 3-month follow-up for adverse outcomes.
  • Statistical analysis using SPSS, with p < 0.05 considered significant.

Main Results:

  • A significant positive correlation was found between myocardial blush grade and ejection fraction improvement (p < 0.05).
  • Higher myocardial blush grade was associated with a significant decrease in adverse outcomes (p < 0.05).
  • Myocardial blush grade and diabetes status independently predicted the percentage increase in ejection fraction (p < 0.05).

Conclusions:

  • High myocardial blush grade is an independent predictor of improved outcomes in ST-elevation myocardial infarction.
  • Myocardial blush grading is a valuable tool for risk stratification and predicting recovery.
  • Optimizing microvascular function, as indicated by blush grade, is key to better patient prognosis.
Abstract

Keywords:
Blush gradePCISTEMITIMI

More Related Videos

Myocardial Infarction and Functional Outcome Assessment in Pigs12:03

Myocardial Infarction and Functional Outcome Assessment in Pigs

Published on: April 25, 2014

28.4K
Delayed Intramyocardial Delivery of Stem Cells after Ischemia Reperfusion Injury in a Murine Model07:50

Delayed Intramyocardial Delivery of Stem Cells after Ischemia Reperfusion Injury in a Murine Model

Published on: September 3, 2020

4.9K

Related Concept Videos

Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
130
Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
518
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
280
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
164
Myocarditis I: Introduction01:21

Myocarditis I: Introduction

Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
251
Imaging Studies for Cardiovascular System I:Echocardiography01:17

Imaging Studies for Cardiovascular System I:Echocardiography

Cardiac imaging studies encompass a wide range of noninvasive and minimally invasive techniques designed to visualize the heart's structure and function in detail. One such technique is echocardiography, which uses high-frequency ultrasound waves to produce detailed images of the heart, known as echocardiograms.
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
642