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Updated: Dec 15, 2025

Continuous Fluorescence-Based Endonuclease-Coupled DNA Methylation Assay to Screen for DNA Methyltransferase Inhibitors
06:07

Continuous Fluorescence-Based Endonuclease-Coupled DNA Methylation Assay to Screen for DNA Methyltransferase Inhibitors

Published on: August 5, 2022

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Novel anticancer drug curaxin CBL0137 impairs DNA methylation by eukaryotic DNA methyltransferase Dnmt3a

Alexander Sergeev1, Andrey Vorobyov1, Marianna Yakubovskaya2

  • 1Department of Chemistry, M. V. Lomonosov Moscow State University, Moscow 119991, Russia.

Bioorganic & Medicinal Chemistry Letters
|July 8, 2020
PubMed

Keywords:
CBL0137CuraxinDNA methylationDnmt3a-CDDoxorubicin

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