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Related Experiment Video

Updated: Dec 15, 2025

Author Spotlight: Leptospira DNA Detection in Water for Environmental Analysis and Disease Surveillance

Author Spotlight: Leptospira DNA Detection in Water for Environmental Analysis and Disease Surveillance

Published on: June 14, 2024

Leptospira and Leptospirosis.

Mathieu Picardeau¹

¹Institut Pasteur, Unité Biologie des Spirochètes, Paris, France. mathieu.picardeau@pasteur.fr.

Methods in Molecular Biology (Clifton, N.J.)

|July 8, 2020

Summary

Leptospira bacteria cause leptospirosis, a zoonotic disease. Recent genomic studies have significantly expanded the known species within the Leptospira genus, impacting our understanding of these unique environmental bacteria.

Area of Science:

Microbiology
Bacteriology
Genomics

Background:

Leptospira spp. are unique bacteria found globally.
Pathogenic Leptospira cause leptospirosis, an emerging zoonotic disease.
Transmission occurs via environmental contamination with infected animal urine.

Purpose of the Study:

To summarize recent taxonomic revisions in Leptospira.
To highlight the impact of whole-genome sequencing on species identification.

Main Methods:

Whole-genome sequencing analysis.
Phylogenetic analysis of Leptospira species.
Review of recent taxonomic literature.

Main Results:

Leptospira taxonomy has been significantly revised.

Keywords:

Genome Pathogenesis Taxonomy Virulence factors

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Last Updated: Dec 15, 2025

Author Spotlight: Leptospira DNA Detection in Water for Environmental Analysis and Disease Surveillance

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Published on: June 14, 2024

Application of CRISPR Interference CRISPRi for Gene Silencing in Pathogenic Species of Leptospira

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Published on: August 14, 2021

Enriching Subcellular Proteins in Leptospira Using a Triton X-114-Based Fractionation Approach

Enriching Subcellular Proteins in Leptospira Using a Triton X-114-Based Fractionation Approach

Published on: August 8, 2025

The number of recognized Leptospira species has considerably increased.

Genomic data provides a robust basis for species delineation.

Conclusions:

Recent genomic studies have reshaped Leptospira taxonomy.
Expanded species diversity requires updated understanding of leptospirosis epidemiology.
Whole-genome sequencing is crucial for accurate bacterial classification.