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Functional movements of the GABA type A receptor

Csilla Várnai1, B W J Irwin2, M C Payne2

  • 1Centre for Computational Biology, University of Birmingham, Birmingham, B15 2TT, UK.

Physical Chemistry Chemical Physics : PCCP
|July 8, 2020
PubMed
Summary

Simulations reveal how GABA receptor binding triggers channel opening. Impulses to GABA binding sites cause opening, with partial opening from single site stimulation, aiding understanding of receptor gating.

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