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Area of Science:

  • Environmental Science
  • Toxicology
  • Ecotoxicology

Background:

  • Mercury (Hg) is a widespread pollutant impacting ecosystems and human health.
  • Elevated selenium (Se) is proposed to counteract Hg toxicity and contamination.
  • Se itself can pose toxicological risks to aquatic life.

Purpose of the Study:

  • To evaluate the scientific evidence for Se's benefits in mitigating Hg contamination and toxicity.
  • To assess if Se reduces methylmercury (MeHg) toxicity in consumers.
  • To determine if environmental Se limits Hg bioaccumulation and methylmercury production.

Main Methods:

  • Comprehensive literature search on Se-Hg interactions.
  • Evaluation of evidence for three key assertions regarding Se's ameliorating effects.
  • Analysis of Se's role in Hg toxicity, bioaccumulation, and microbial methylation.

Main Results:

  • Limited or ambiguous scientific support was found for Se reducing MeHg toxicity.
  • Evidence is insufficient to confirm environmental Se reduces Hg bioaccumulation or biomagnification.
  • Uncertainty remains regarding Se's inhibition of Hg bioavailability and microbial methylation.

Conclusions:

  • Significant scientific uncertainties and knowledge gaps exist regarding Se's mediation of Hg.
  • More data is required to support revising fish consumption advisories based on Se:Hg ratios.
  • Further research is needed to validate Se amendments for remediating Hg-contaminated ecosystems.