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Related Concept Videos

Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

152
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
152
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

164
In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
164
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

110
Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
110
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

126
Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
126
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

141
As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
141
Aging01:26

Aging

490
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
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Related Experiment Video

Updated: Dec 15, 2025

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains
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Geriatrics Scholarly Concentration Programs Among U.S. Medical Schools.

Lindsay A Wilson1, Meredith A Gilliam1, Natalie L Richmond2

  • 1Division of Geriatric Medicine, Department of Internal Medicine, University of North Carolina School of Medicine at Chapel Hill, Chapel Hill, North Carolina, USA.

Journal of the American Geriatrics Society
|July 8, 2020
PubMed
Summary

Few U.S. medical schools offer Geriatric Scholarly Concentration Programs (GSCPs). These programs provide valuable geriatric training and may boost interest in geriatric subspecialty careers for interested students.

Keywords:
educationmedical schoolscholarly concentration program

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Area of Science:

  • Geriatric Medicine
  • Medical Education
  • Healthcare Workforce Development

Background:

  • Limited exposure to geriatric competencies in standard medical school curricula.
  • Need to foster interest in geriatric medicine subspecialties.
  • Importance of specialized training for an aging population.

Purpose of the Study:

  • To identify and describe Geriatric Scholarly Concentration Programs (GSCPs) in U.S. medical schools.
  • To understand the structure, components, and outcomes of existing GSCPs.

Main Methods:

  • Systematic internet search, forum postings, and word-of-mouth to identify GSCPs.
  • Online surveys completed by GSCP directors.
  • Interviews with key faculty from representative programs.

Main Results:

  • Nine GSCPs identified; eight responded to the survey.
  • Programs featured mentoring, specialized clinical experiences, and research.
  • Common challenges included low student interest and faculty availability, yet student satisfaction was high.
  • Half of graduates from reporting programs pursued residencies with geriatric training options.

Conclusions:

  • Geriatric Scholarly Concentration Programs are scarce in U.S. medical schools.
  • GSCPs can enhance geriatric competencies for interested students.
  • These programs show potential to increase the number of physicians entering geriatric subspecialties.