Related Experiment Video
Updated: Dec 15, 2025

Long-term Behavioral and Reproductive Consequences of Embryonic Exposure to Low-dose Toxicants
Published on: March 6, 2018
Exposure to New Emerging Bisphenols Among Young Children in Switzerland
Fiorella Lucarini1, Tropoja Krasniqi1, Gaëlle Bailat Rosset2
1Department of Biomedical Sciences, University of Lausanne, 1011 Lausanne, Switzerland.
Insights
Young children in Switzerland are exposed to bisphenol analogues, including bisphenol C (BPC) and bisphenol M (BPM). Urinary levels of bisphenol S (BPS) and bisphenol F (BPF) exceeded those of bisphenol A (BPA).
Area of Science:
- Environmental Health
- Toxicology
- Pediatric Health
Background:
- Restrictions on bisphenol A (BPA) have led to increased use of analogues.
- Exposure to these emerging bisphenol analogues in young children is not well understood.
- Urinary biomonitoring is crucial for assessing chemical exposure in vulnerable populations.
Purpose of the Study:
- To characterize infant and toddler exposure to BPA and 14 bisphenol analogues.
- To establish a baseline for bisphenol exposure in Swiss children.
- To inform public health strategies for exposure reduction.
Main Methods:
- Non-invasive collection of infant and toddler urine samples from diapers (n=109) in Swiss daycare centers.
- Analysis of urinary concentrations of BPA and 14 emerging bisphenol analogues.
- Statistical analysis to identify correlations between bisphenol levels and demographic factors.
Main Results:
- Bisphenols were detected in 47% of samples.
- Bisphenol C (BPC) and bisphenol M (BPM) were the most frequently detected analogues.
- Mean urinary concentrations of bisphenol S (BPS) and bisphenol F (BPF) were higher than BPA.
- A negative correlation was found between BPM concentration and age.
Conclusions:
- This study provides the first characterization of bisphenol exposure in Swiss infants and toddlers.
- BPS and BPF are significant urinary bisphenol metabolites in this population.
- Findings support the need for biomonitoring and targeted exposure reduction strategies for young children.
Abstract:
Restrictions on the use of bisphenol A (BPA) in consumer products led to its replacement by various bisphenol (BP) analogues, yet young children's exposure to these analogues has been poorly characterized so far. This study aimed to characterize infants' and toddlers' exposure to BPA and 14 emerging BP analogues (i.e., bisphenol AF, bisphenol AP, bisphenol B, bisphenol BP, bisphenol C (BPC), bisphenol E, bisphenol F (BPF), bisphenol G, bisphenol M (BPM), bisphenol P, bisphenol PH, bisphenol S (BPS), bisphenol TMC, and bisphenol Z). We extracted infants' and toddlers' urine from diapers (n = 109) collected in Swiss daycare centers as a practical and noninvasive alternative approach to urinary biomonitoring. Bisphenols were present in 47% of the samples, with BPC and BPM being the most frequently detected (23% and 25% of all samples, respectively). The mean concentrations of urinary BPS and BPF were greater than that of BPA. This contrasts with data reported previously. Furthermore, statistical analysis revealed a significant and negative correlation between urinary BPM concentration and the population's age. Our results provide a first characterization of infants' and toddlers' exposure to bisphenols in Switzerland. This knowledge can be used to support ongoing biomonitoring studies and to prioritize exposure reduction and prevention strategies.
More Related Videos
08:28Assessment of the Effects of Endocrine Disrupting Compounds on the Development of Vertebrate Neural Network Function Using Multi-electrode Arrays
Published on: April 26, 2018
08:12Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants
Published on: March 29, 2018
Related Concept Videos
Teratogenicity
Types of Toxins
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
Pharmacokinetics in Pediatric Patients: Drug Metabolism