Related Experiment Video
Updated: Dec 15, 2025
08:41
Lateral Chronic Cranial Window Preparation Enables In Vivo Observation Following Distal Middle Cerebral Artery Occlusion in Mice
Published on: December 29, 2016
12.1K
Mesial bifrontal stroke presenting as isolated spontaneous confabulations
Vardan Nersesjan1, Henrik Gutte Bogwardt2, Daniel Kondziella3,4
1Department of Neurology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark vardan.nersesjan@gmail.com.
Practical Neurology
|July 9, 2020
Summary
A stroke affecting the frontal lobe caused a man to experience spontaneous confabulation and memory issues. This case highlights the link between brain lesions, confabulation, and potential overlaps with dreaming states.
Area of Science:
- Neurology
- Neuroscience
- Neuroradiology
Background:
- Spontaneous confabulation is a rare neurological symptom.
- Atrial fibrillation can increase stroke risk.
- Frontal lobe lesions can cause cognitive deficits.
Observation:
- A 52-year-old man with atrial fibrillation presented with confabulation, memory deficits, and frontal release signs.
- Brain MRI revealed bifrontal mesial ischemic strokes.
- Angiography showed both anterior cerebral arteries supplied by the left internal carotid artery.
Findings:
- Isolated spontaneous confabulation is a rare stroke presentation.
- Orbitofrontal cortex lesions may be associated with confabulation.
- Medial frontal lobe hypometabolism during REM sleep suggests overlap between dreaming and confabulation.
Implications:
- Understanding the neuroanatomy of confabulation is crucial for diagnosis.
- This case emphasizes the diverse clinical manifestations of stroke.
- Further research into the relationship between sleep, dreaming, and confabulation is warranted.
