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Accuracy of methods for diagnosing heart diseases in cats

Tanarut Laudhittirut1, Natrada Rujivipat1, Kornnicha Saringkarisate1

  • 1Department of Veterinary Medicine, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, Thailand.

Veterinary World
|July 9, 2020
PubMed

Insights

Diagnosing heart disease in cats is more reliable when multiple tests are used. The N-terminal Pro-B-type natriuretic peptide (NT-proBNP) point-of-care test showed optimal accuracy for feline heart disease diagnosis.

Area of Science:

  • Veterinary Cardiology
  • Diagnostic Imaging
  • Biomarkers in Animal Health

Background:

  • Accurate diagnosis of heart disease in cats is crucial for effective treatment.
  • Current diagnostic methods vary in accuracy and reliability.
  • Evaluating novel and established diagnostic tools is essential.

Purpose of the Study:

  • To assess the accuracy of seven different diagnostic methods for feline heart disease.
  • To compare the effectiveness of imaging techniques and biomarker tests.
  • To identify the most reliable diagnostic approach for cats.

Main Methods:

  • Retrospective analysis of data from 58 cats (38 with heart disease, 20 healthy).
  • Evaluation of seven diagnostic methods: Vertebral Heart Score (VHS) variations, cardiac dimensions ratios, NT-proBNP point-of-care test, and subjective assessments (ultrasound and radiography).
  • Echocardiography served as the gold standard; sensitivity, specificity, and predictive values were calculated using cross-tabulation.

Main Results:

  • The N-terminal Pro-B-type natriuretic peptide (NT-proBNP) point-of-care test demonstrated optimal accuracy in diagnosing heart disease in cats.
  • Subjective ultrasonographic assessment of left atrial size was effective for diagnosing hypertrophic cardiomyopathy and congestive heart failure.
  • Combining multiple diagnostic tests increased the overall reliability of the diagnosis.

Conclusions:

  • The NT-proBNP point-of-care test is a valuable tool for feline heart disease diagnosis.
  • Integrating various diagnostic methods enhances diagnostic confidence and accuracy.
  • Further research into multimodal diagnostic strategies is warranted for improved feline cardiac care.
Abstract

Keywords:
N-terminal Pro-B-type natriuretic peptidecardiac disease diagnosisthoracic radiographyultrasonography

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