Related Experiment Video
Updated: Dec 15, 2025

Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty
Published on: October 6, 2016
Hemodynamic Effects of a Multidisciplinary Geriatric Rehabilitation Program
Nikolaos Pagonas1,2, Frederic Bauer1, Laura Zappe1
1University Hospital Marien Hospital Herne, Department of Internal Medicine I, Ruhr-University Bochum, Bochum, Germany.
Geriatric rehabilitation programs improve mobility and daily living activities in elderly patients. While systolic blood pressure showed a mild reduction, the program did not significantly impact other cardiovascular measures like arterial stiffness.
Area of Science:
- Gerontology
- Cardiovascular Medicine
- Rehabilitation Science
Background:
- Geriatric rehabilitation programs focus on enhancing mobility and functional autonomy in older adults.
- The cardiovascular effects of these programs are not well-established.
- Physical exercise is known to benefit cardiovascular health, including blood pressure reduction.
Purpose of the Study:
- To investigate the hemodynamic effects of a standardized geriatric rehabilitation program.
- To assess changes in peripheral blood pressure, central aortic blood pressure, and arterial stiffness.
Main Methods:
- A prospective study involving 74 hospitalized geriatric rehabilitation patients.
- Measurements included peripheral and central blood pressure, 24-hour ambulatory blood pressure, heart rate, and pulse wave velocity.
- The rehabilitation program consisted of 4-5 weekly sessions of individualized physical activity for at least 30 minutes each.
Main Results:
- The program significantly improved mobility (Timed Up & Go) and activities of daily living (Barthel index).
- Peripheral systolic blood pressure decreased significantly from 135.4±19.0 mmHg to 129.0±18.4 mmHg (p=0.03).
- No significant changes were observed in peripheral diastolic blood pressure, central aortic blood pressure, 24-hour ambulatory blood pressure, heart rate, or pulse wave velocity.
Conclusions:
- The standardized geriatric rehabilitation program effectively enhanced patient mobility and daily functioning.
- A mild, statistically significant reduction in peripheral systolic blood pressure was observed.
- The program did not demonstrate significant effects on 24-hour ambulatory blood pressure or arterial stiffness.
Related Concept Videos
Pharmacodynamics in Geriatric Patients: Effects of Age
Drug Dosing: Geriatric Patients
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion
Heart Failure VI: Adjunct Therapies
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution