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A severe refractory COVID-19 patient responding to convalescent plasma; A case series

Hadi Mohammed Abdullah1, Hersh H Hama-Ali2, Sabah Nasraddin Ahmed3

  • 1Shar Hospital, Sulaimani, Kurdistan, Iraq.

Annals of Medicine and Surgery (2012)
|July 9, 2020
PubMed

Insights

Convalescent plasma (CP) shows promise for treating severe COVID-19. Two patients with severe coronavirus disease 2019 improved clinically and radiologically after CP infusion.

Area of Science:

  • Infectious Diseases
  • Virology
  • Immunology

Background:

  • No specific antiviral drug is currently approved for 2019 novel coronavirus.
  • Severe cases of COVID-19 require effective therapeutic interventions.

Purpose of the Study:

  • To describe two severe cases of COVID-19 treated with convalescent plasma.
  • To evaluate the potential efficacy of convalescent plasma in severe COVID-19.

Main Methods:

  • Two male patients diagnosed with severe COVID-19 were treated with convalescent plasma.
  • Clinical and radiological improvements were monitored post-infusion.

Main Results:

  • Both patients showed clinical and radiological improvement after convalescent plasma infusion.
  • Patients were discharged in good condition with negative virology tests.

Conclusions:

  • Convalescent plasma may be an effective therapy for severe COVID-19.
  • Further research is warranted to confirm the efficacy of convalescent plasma.
Abstract

Keywords:
COVID-19Convalescent plasmaCoronavirusSARS-CoV-2

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